Velesco Pharmaceutical Services was founded by Pfizer pharmaceutical scientists from Michigan's former R&D facility. They are a CMC (Chemistry, Manufacturing, and Controls) contract research organization, specializing in analytical chemistry, drug formulation, clinical supply manufacture, and more. Velesco is now based in Wixom, MI with an additional facility in Kalamazoo, MI.

Tissue Regeneration Systems (TRS) is developing and commercializing skeletal reconstruction and bone regeneration technologies (licensed from the Universities of Michigan and Wisconsin). The company's specific 3D printing scaffold technology was acquired in 2017 by DePuy Synthes Products, Inc., a subsidiary of Johnson & Johnson.

RetroSense developed a type of gene therapy to restore vision in patients with blindness. The company and its technologies were acquired by Allergan in 2016.

Lycera is focused on developing medicines for autoimmune disorders and cancers. Their novel treatments are based on small molecules designed to modulate immune system functions. The company has several locations, but is headquartered in Ann Arbor, MI.

One of MLSIC's original tenants, Esperion is now based in Ann Arbor, MI. A publicly-traded pharmaceutical company, their focus is on developing non-statin drugs that lower LDL-C - a type of "bad" cholesterol.

Celsee, Inc. develops, manufactures, and markets integrated comprehensive single-cell analysis solutions that can accurately identify, analyze, and retrieve viable cells directly from blood and tissue. In 2019, Celsee, Inc. opened their headquarters in Ann Arbor, MI.

Algal Scientific developed technologies and processes to produce nutrients from algae and wastewater. Kemin Industries acquired their beta-glucan manufacturing technology. Company now based in Plymouth, MI.

ClynProject Consulting brings a broad knowledge of experience across therapeutics areas. Established in 2017, and located in Southeastern Michigan. Specializing in clinical project management and clinical monitoring. Regionally based, and follows a business model that allows to offer quality professional services with low overhead at reasonable, competitive industry pricing.

Delphinus' focus on early detection of breast cancer led them to the development of their 3D breast ultrasound technology, SoftVue(TM). They are now based in Novi, MI. The company began as a "spin-off" from the Karmanos Cancer Institute and Wayne State University.

Stonebridge is an independent testing and development laboratory serving the coatings and related industries, offering project design and management, product development and testing, problem solving, competitive product testing and analysis, deformulation, failure analysis, and expert witness services. Specialties include architectural, industrial maintenance, industrial OEM, automotive refinish, and automotive OEM coatings.

Penrose Therapeutx is a chemistry-driven pharmaceutical company that employs a mechanistic and rational approach in bringing oncologic solutions to the patients of today and tomorrow. The company was founded by a group of individuals who value beneficence above all else. Penrose Therapeutx’s intellectual property will allow an unprecedented drug discovery platform in the area of oncology that views cancer as a pathological redox disease. At Penrose Therapeutx, our goal is to improve cancer-related outcomes that are accompanied by unmatched safety and a cost-effective profile for patients and their families.