Our History

April 1991

Diversey Lever, Inc. constructs manufacturing facility in Plymouth, Michigan. This is the future home of MLSIC.

January 2000

Building is purchased by Pfizer.

March 2004

Pfizer spends $11.5 million in building improvements and modifications to create a home for the newly-acquired Esperion Therapeutics.

May 1, 2006

The building reopens as Pfizer's Esperion facility.

January 22, 2007

Pfizer announces the closure of three Michigan operations, including the Plymouth, MI Esperion Therapeutics facility.

September 30, 2007

Pfizer's Esperion facility closes its doors.

May 1, 2008

The facility is reopened as Michigan Life Science and Innovation Center (MLSIC), a life sciences business incubator aimed at keeping talent in Michigan after the loss of Pfizer. With the assistance of Ann Arbor SPARK, Wayne County, MEDC, various local officials & organizations, and private funding, the building was purchased. MLSIC immediately became the home of several start-up companies founded by former Pfizer employees. Ann Arbor SPARK oversees and manages the facility.

November 1, 2012

Ann Arbor SPARK ceases management of MLSIC, handing oversight to MEDC Entrepreneurship & Innovation.

October 1, 2018

The MEDC transitions management of the Michigan Life Science and Innovation Center to MLSIC, LLC.


Michigan Life Science and Innovation Center (MLSIC) is southeastern Michigan’s premier home for life science and other high-tech, innovation based startup businesses.